Iron metabolism in copper-deficient rats

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Iron metabolism in copper-deficient rats.

I . The effects of ingestion of diets deficient in both copper and iron on storage of these elements and on the red cell indices have been studied in rats. 2. Injection of Cu into rats whose stores of Cu had been virtually exhausted resulted in a temporary increase in the concentration of plasma Fe and depletion of the Fe stored in the liver. Storage of Fe in the spleen seemed to be affected so...

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Iron metabolism in copper-deficient swine.

The way in which iron is handled by the duodenal mucosa, the reticuloendothelial system, the hepatic parenchymal cell, and the normoblast was investigated in copper-deficient swine.Copper-deficient swine failed to absorb dietary iron at the normal rate. Increased amounts of stainable iron were observed in fixed sections of duodenum from such animals. When (59)iron was administered orally, the m...

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Effects of iron on copper metabolism and copper on iron metabolism in rats.

OWEN, CHARLES A., JR. Effects of iron on copper metabolism and copper on iron metabolism in rats. Am. J. Physiol. 224(3): 514-518. 1973.-Male Sprague-Dawley rats were fed whole-milk powder (Cu ,Fe deficient), milk powder plus Cu in the drinking water (Fe deficient), or milk powder plus iron in the drinking water (Cu deficient). Studies with 67Cu were carried out for the most part after the rats...

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Normal folic acid metabolism in iron-deficient rats.

I . Weanling rats were fed on an iron-deficient diet without added folic acid and litter-mate controls received the same diet supplemented with Fe. Groups of deficient and control animals were killed at intervals of up to 88 days and glutamate formiminotransferase activity in liver and folic acid activity in liver and serum were measured. 2. No differences were found between the results from th...

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Tissue levels of iron, copper, zinc and magnesium in iron deficient rats

The effects of iron deficiency on the levels of iron, copper, zinc and magnesium in the brain, liver, kidney, heart and lungs of albino rats (Rattus novergicus) was investigated. Forty rats were divided into two groups and the first group was fed a control diet containing 1.09g iron/kg diet while the test group was fed diet containing 9ppm iron/kg diet. Tissue iron level reduced in all the diet...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 1971

ISSN: 0007-1145,1475-2662

DOI: 10.1079/bjn19710062